CANNABIS AND PAIN

The pain is a part of everyday life. This can appear at any time and without asking for our approval. This unpredictable or uncontrollable aspect caught our attention. Therefore, we have decided to focus on the subject. In fact, what is pain? What can be the magnitude of this within the population? What are the subject matter experts saying? The Can cannabis help relieve the pain ? So let’s provide answers to these questions below.

A STOP TO BETTER UNDERSTAND THE PAIN

The issue of pain is delicate. So, it seems important to us to convene several profiles of people with knowledge on the subject. Thus, we will have both a comprehensive and diverse understanding.

PAIN SEEN BY A JOURNALIST

Marie-Céline Ray, via Futura-Sciences , defines pain as “(…) a painful sensation felt at a point of the body”. In the process, she adds, against all expectations that this (pain) is important for each individual. How to explain this? Indeed, “Some people suffer from a genetic disease that reduces or eliminates pain: the insensitivity to pain syndrome,” she says. Clearly, pain is both unpleasant and vital.

In addition to the above, she distinguishes two main types of pain. Among others, acute pain and chronic pain . In fact, the former are painful sensations of short duration. Along these lines, it could be pain when you put your hand on a heated surface. The latter, on the other hand, extend over time. Some people can experience them for several months. By way of illustration, fibromyalgia.

PAIN SEEN BY A PHARMACIST

In fact, people prone to pain tend to go for self-medication. Therefore, they are in constant contact with pharmacists. In other words, we suggest that you stop by an interview conducted by the Analgesia Institute, on the occasion of World Pain Day. Sandrine JALLET, dispensary pharmacist in Issoire answers a few questions and provides an overview of her daily life with patients suffering from pain.

PAIN SEEN BY A GENERAL PRACTITIONER

Following the previous looks, we suggest you move up a notch. Indeed, this time, let’s see what pain is for a general practitioner. In order to achieve this, we take another interview conducted by the Analgesia Institute on the occasion of World Pain Day. Laurent LETRILLIART, General practitioner, Professor at the University Claude Bernard Lyon 1 and researcher in the HESPER unit, lends himself to the game of questions and answers. 

PAIN SEEN BY AN ALGOLOGIST

So let’s finish our overview of looks at pain! Here, let us call on a professional specialized in the matter. Pr Nadine ATTAL, algologist at the CHU Amboise Paré and researcher in the Inserm U987 unit, talks to us. 

At the end of this interview, the Professor specifies that despite advanced treatments, some pains manage to resist. So the space is open for parallel solutions. In that vein? How can cannabis help? Can the latter help relieve pain?

CANNABIS AND PAIN: LET’S TALK ABOUT IT!

The most curious among us have already browsed many pages on the web. Why ? To find out if cannabis relieves pain . The answer ? You could imagine: it is Yes. On pain of losing yourself in the very vast universe of this substance, we suggest that you make stops on cannabis molecules that can help against pain .

?-9-TETRAHYDROCANNABINOL

It is much more called THC. In fact, it is the most abundant cannabinoid in the cannabis plant. We give you more details on this molecule.

  • Formula: C??H??O?
  • Molecular formula: C 21 H 30 O 2 ;
  • Molar mass: 314.45 g / mol
  • IUPAC Name: (-) – (6aR, 10aR) -6,6,9-trimethyl- 3-pentyl-6a, 7,8,10a-tetrahydro- 6H-benzo [c] chromen-1-ol
  • IUCPAC name: (6aR, 10aR) -6,6,9-trimethyl-3-pentyl-6a, 7,8,10a-tetrahydrobenzo, chromen-1-ol
  • Solubility: Glycerol, Alcohol, Acetone, Base oil

This is because THC has analgesic and therapeutic properties. Taking it in small amounts over the short term can help relieve pain without side effects. Nevertheless, it is necessary to know that a prolonged or large quantity intake can cause psychotropic effects. This information does not replace medical advice. In addition, we invite you to refer to the regulations of your country on the consumption of products containing THC. The maximum amount varies from nation to nation. Failure to comply with this legislation can lead to severe penalties.

CANNFLAVIN A AND CANNFLAVIN B

The cannflavine A and cannflavine B are probably the least known molecules of the cannabis plant. In fact, they are flavonoids. They were discovered by a team of researchers from the University of Guelph, Canada. According to them (these researchers), these molecules would be more powerful than aspirin. Their report echoes this. Indeed, their presence in small quantities in the cannabis plant justifies the fact that they are very little known, as painkillers. Deeper research on these molecules, which also help relieve pain, is underway.

CANNABIDIOL

This molecule is better known under the name of CBD . In fact, it is certainly the most famous, as of this writing, of the molecules in cannabis. We give you its details below.

  • Formula: C 21 H 30 O 2
  • Molecular formula: C 21 H 30 O 2 ;
  • Molar mass: 314.464 g / mol
  • CAS Number: 13956-29-1
  • IUPAC Name: 2–5-pentylbenzene-1,3-diol
  • PubChem CID: 644019

The therapeutic virtues of CBD are well known. These no longer need to be touted. Let’s focus on its benefit for pain-prone patients.

Indeed, a study was carried out by a team of scientists from the Research Institute of the McGill University Health Center (RI-MUHC) and McGill University. Under the leadership of Dr Gabriella Gobbi , this team shows that CBD works through the mechanism that binds the receptors involved in pain (TRPV1). On this, Danilo De Gregorio, postdoctoral fellow at McGill University explains.

“We have found that in animal models of chronic or neuropathic pain, low doses of CBD given for seven days relieves pain and anxiety, two symptoms often associated with this condition.”

Dr Gabriella Gobbi to add:

“Our findings shed light on the mechanism of action of CBD; they demonstrate that this substance can be used as a medicine without producing the dangerous side effects associated with THC… ”

In the same vein, she falls by affirming:

“There is limited data to suggest that CBD relieves pain in humans, but more, larger clinical studies are needed …”

Leave a Reply

Your email address will not be published. Required fields are marked *